Pamela Reinagel’s foundational training was in experimental molecular biology, biochemistry, and genetics. She earned her BS in Genetics at Carnegie Mellon University and PhD in Biochemistry at Harvard University. She then changed fields, obtaining postdoctoral training in theoretical neuroscience with Markus Meister at Harvard and with Christof Koch at CalTech, and in experimental neuroscience with Clay Reid at Harvard Medical School. She started her own lab in the Biology Division at UCSD in 2003. Currently her lab studies the computational and theoretical neuroscience of decision-making under conditions of uncertainty, primarily through behavioral experiments with rats. Recently she has become interested in the unique methods of scientific inference used in modern experimental biology, drawing on insights from her nearly four decades at the bench doing basic research in diverse biological systems.